Podcast Series

Formulation Approaches and Techniques

18 - 20 May

Podcast Series

Formulation Approaches and Techniques

EPISODE ONE

Solid Oral Dosage Forms

Increasing demand for personalised medicines is transforming solid oral dosage formulation, to the extent that the limitations of conventional tableting machines are being exposed as the industry looks towards a more flexible approach to facilitate the design and production of the bespoke medicines of the future.

With the rise of additive manufacturing, including 3D printing, how can formulators best utilise this promising technology to produce bespoke drug delivery devices, such as solid oral dosage forms?

Does the use of additive manufacturing allow more flexibility in the design process?

EPISODE TWO

Early Phase Formulations: Stability and Bioavailability

The use of liquid formulations of drug candidates is popular in Phase I trials due to their being faster and cheaper to develop as well as a way of maximising oral bioavailability. Focus on reformulating to a more commercially suitable format such as solid dose usually occurs in later stage studies.

However, there is a growing consensus that if the two key attributes of stability and bioavailability are to be taken into full consideration, it is better to start considering the solid dose form during formulation development for first in human trials.

Why are stability and bioavailability so important in early stage formulation? What are the knock-on benefits of focusing on stability and bioavailability early on?

EPISODE 3

Early Phase Formulations: Stability and Bioavailability

Why are stability and bioavailability so important in early stage formulation? What are the knock-on benefits of focusing on stability and bioavailability early on?